CUSIP No. 140755109
|
Schedule 13G
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Page 2 of 11
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1
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NAME OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Ascent Biomedical Ventures I, L.P.
|
|||
2
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CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a) o
(b) x
|
|
||
3
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SEC USE ONLY
|
|||
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
|
|||
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
|
5
|
SOLE VOTING POWER
Not applicable
|
||
6
|
SHARED VOTING POWER
963,896
|
|||
7
|
SOLE DISPOSITIVE POWER
Not applicable
|
|||
8
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SHARED DISPOSITIVE POWER
963,896
|
|||
9
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AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
963,896
|
|||
10
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CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions)
|
x (1)
|
||
11
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PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
4.3%
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|||
12
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TYPE OF REPORTING PERSON (See Instructions)
PN
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CUSIP No. 140755109
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Schedule 13G
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Page 3 of 11
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1
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NAME OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Ascent Biomedical Ventures I Annex, L.P.
|
|||
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a) o
(b) x
|
|
||
3
|
SEC USE ONLY
|
|||
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
|
|||
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
|
5
|
SOLE VOTING POWER
Not applicable
|
||
6
|
SHARED VOTING POWER
105,730
|
|||
7
|
SOLE DISPOSITIVE POWER
Not applicable
|
|||
8
|
SHARED DISPOSITIVE POWER
105,730
|
|||
9
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AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
105,730
|
|||
10
|
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions)
|
x (2)
|
||
11
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PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
0.4%
|
|||
12
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TYPE OF REPORTING PERSON (See Instructions)
PN
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CUSIP No. 140755109
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Schedule 13G
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Page 4 of 11
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1
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NAME OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Ascent Biomedical Ventures I NY, L.P.
|
|||
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a) o
(b) x
|
|
||
3
|
SEC USE ONLY
|
|||
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
|
|||
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
|
5
|
SOLE VOTING POWER
Not applicable
|
||
6
|
SHARED VOTING POWER
604,428
|
|||
7
|
SOLE DISPOSITIVE POWER
Not applicable
|
|||
8
|
SHARED DISPOSITIVE POWER
604,428
|
|||
9
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AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
604,428
|
|||
10
|
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions)
|
x (3)
|
||
11
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PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
2.7%
|
|||
12
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TYPE OF REPORTING PERSON (See Instructions)
PN
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CUSIP No. 140755109
|
Schedule 13G
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Page 5 of 11
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1
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NAME OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
ABV, LLC
|
|||
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a) o
(b) x
|
|
||
3
|
SEC USE ONLY
|
|||
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
|
|||
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
|
5
|
SOLE VOTING POWER
Not applicable
|
||
6
|
SHARED VOTING POWER
1,674,054 (4)
|
|||
7
|
SOLE DISPOSITIVE POWER
Not applicable
|
|||
8
|
SHARED DISPOSITIVE POWER
1,674,054 (4)
|
|||
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,674,054 (4)
|
|||
10
|
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions)
|
x (5)
|
||
11
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PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
7.4%
|
|||
12
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TYPE OF REPORTING PERSON (See Instructions)
OO
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CUSIP No. 140755109
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Schedule 13G
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Page 6 of 11
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1
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NAME OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Geoffrey W. Smith
|
|||
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a) o
(b) x
|
|
||
3
|
SEC USE ONLY
|
|||
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
United States
|
|||
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
|
5
|
SOLE VOTING POWER
Not applicable
|
||
6
|
SHARED VOTING POWER
1,674,054 (6)
|
|||
7
|
SOLE DISPOSITIVE POWER
Not applicable
|
|||
8
|
SHARED DISPOSITIVE POWER
1,674,054 (6)
|
|||
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,674,054 (6)
|
|||
10
|
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions)
|
x (7)
|
||
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
7.4%
|
|||
12
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TYPE OF REPORTING PERSON (See Instructions)
IN
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CUSIP No. 140755109
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Schedule 13G
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Page 7 of 11
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1
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NAME OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Steve Hochberg
|
|||
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a) o
(b) x
|
|
||
3
|
SEC USE ONLY
|
|||
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
United States
|
|||
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
|
5
|
SOLE VOTING POWER
Not applicable
|
||
6
|
SHARED VOTING POWER
1,674,054 (8)
|
|||
7
|
SOLE DISPOSITIVE POWER
Not applicable
|
|||
8
|
SHARED DISPOSITIVE POWER
1,674,054 (8)
|
|||
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,674,054 (8)
|
|||
10
|
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions)
|
x (9)
|
||
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
7.4%
|
|||
12
|
TYPE OF REPORTING PERSON (See Instructions)
IN
|
CUSIP No. 140755109
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Page 8 of 11
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(a)
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Name of Issuer:
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(b)
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Address of Issuer’s Principal Executive Offices:
|
(a)
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Name of Person Filing:
|
|
(i)
|
Ascent Biomedical Ventures I, L.P. (“Ascent”)
|
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(ii)
|
Ascent Biomedical Ventures I Annex, L.P. (“Ascent Annex”)
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(iii)
|
Ascent Biomedical Ventures I NY, L.P. (“Ascent NY”)
|
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(iv)
|
ABV, LLC (“ABV”)
|
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(v)
|
Geoffrey W. Smith (“Geoffrey Smith”)
|
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(vi)
|
Steve Hochberg (“Steve Hochberg” and together with Ascent, Ascent Annex, Ascent NY, ABV, and Geoffrey Smith, the “Reporting Persons”)
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(b)
|
Address of Principal Business Office or, if none, Residence:
|
|
(i)
|
142 West 57th Street, 4A, New York, NY 10019
|
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(ii)
|
142 West 57th Street, 4A, New York, NY 10019
|
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(iii)
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142 West 57th Street, 4A, New York, NY 10019
|
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(iv)
|
142 West 57th Street, 4A, New York, NY 10019
|
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(v)
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142 West 57th Street, 4A, New York, NY 10019
|
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(vi)
|
142 West 57th Street, 4A, New York, NY 10019
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(c)
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Citizenship:
|
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(i)
|
Delaware limited liability partnership
|
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(ii)
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Delaware limited liability partnership
|
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(iii)
|
Delaware limited liability partnership
|
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(iv)
|
Delaware limited liability company
|
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(v)
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United States Citizen
|
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(vi)
|
United States Citizen
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CUSIP No. 140755109
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Page 9 of 11
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(d)
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Title of Class of Securities:
|
(e)
|
CUSIP Number:
|
(a)
|
Amount Beneficially Owned**:
|
(b)
|
Percent of Class**:
|
(c)
|
Number of shares as to which the person has**:
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CUSIP No. 140755109
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Page 10 of 11
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CUSIP No. 140755109
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Page 11 of 11
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Dated: February 10, 2014 | ASCENT BIOMEDICAL VENTURES I, L.P. | ||
By: |
ABV, LLC
its general partner |
||
/s/ Steve Hochberg | |||
Signature | |||
Director | |||
Name/Title | |||
ASCENT BIOMEDICAL VENTURES I ANNEX, L.P. | |||
By: |
ABV, LLC
its general partner
|
||
/s/ Steve Hochberg | |||
Signature | |||
Director | |||
Name/Title | |||
ASCENT BIOMEDICAL VENTURES I NY, L.P. | |||
By: |
ABV, LLC
its general partner
|
||
/s/ Steve Hochberg | |||
Signature | |||
Director | |||
Name/Title | |||
ABV, LLC | |||
/s/ Steve Hochberg | |||
Signature | |||
Director | |||
Name/Title | |||
GEOFFREY W. SMITH
|
||
/s/ Geoffrey W. Smith
|
||
Signature
|
||
STEVE HOCHBERG
|
||
/s/ Steve Hochberg
|
||
Signature
|
ASCENT BIOMEDICAL VENTURES I, L.P. | |||
By: |
ABV, LLC
its general partner |
||
/s/ Steve Hochberg | |||
Signature | |||
Director | |||
Name/Title | |||
ASCENT BIOMEDICAL VENTURES I ANNEX, L.P. | |||
By: |
ABV, LLC
its general partner
|
||
/s/ Steve Hochberg | |||
Signature | |||
Director | |||
Name/Title | |||
ASCENT BIOMEDICAL VENTURES I NY, L.P. | |||
By: |
ABV, LLC
its general partner
|
||
/s/ Steve Hochberg | |||
Signature | |||
Director | |||
Name/Title | |||
ABV, LLC | |||
/s/ Steve Hochberg | |||
Signature | |||
Director | |||
Name/Title | |||
GEOFFREY W. SMITH
|
||
/s/ Geoffrey W. Smith
|
||
Signature
|
||
STEVE HOCHBERG
|
||
/s/ Steve Hochberg
|
||
Signature
|
||
Name
|
Amount Beneficially Owned
|
James E. Flynn (1)
|
350,000
|
Deerfield Mgmt, L.P. (1)
|
350,000
|
Deerfield Management Company, L.P. (1)
|
350,000
|
Deerfield Special Situations Fund, L.P.
|
193,200
|
Deerfield Special Situations International Master Fund, L.P.
|
156,800
|
|
(1)
|
Comprised of shares held by Deerfield Special Situations Fund, L.P. and Deerfield Special Situations International Master Fund, L.P.
|